There was a time when man passed by things we could not see. Many things are invisible, but that doesn't mean they don't exist. Yet scientists have known for centuries that the insides of all living things are made up of tiny cells. Man has long wanted to see the invisible, challenge the impossible and discover the many mysteries of life. Is there any importance of microscope? This is a great essay question as we will now take a look at the history of the invention of the microscope and the impact it has had on the field of cell biology. It's quite fascinating to think that our eyes are as powerful as microscopes so much so that we can even see all the germs crawling on our hands. Say no to plagiarism. Get a tailor-made essay on "Why Violent Video Games Shouldn't Be Banned"? Get an Original Essay The invention of microscopes and today's science have opened up a whole new dimension in science. We now recognize that there are many things happening on a microscopic scale that can help us live more effectively. Microscope is the aggregate of two words, "micro" meaning small and "scope" meaning sight. Using microscopes, scientists have been able to discover the existence of microorganisms, learn about the shape of cells, and see the smallest components of plants, animals, and fungi. Around 1000 AD the first imaginative and prescient aid (the inventor unknown) referred to as the study stone was invented. It was a glass sphere that enlarged when placed on reading material, circa 1284 - Italian, Salvino D'Armate is credited with inventing the first wearable eyeglasses, 1590 Two Dutch eyeglass makers, Zaccharias Janssen and his son Hans Janssen, experimented with a pair of lenses placed in a tube. The Janssens found that objects viewed in front of the tube appeared greatly magnified, making each the precursor to the compound microscope and telescope, 1665 – English physicist Robert Hooke looked at a fragment of cork through a microscope lens and observed some "pores" or " cells" in it. In 1674, Anton van Leeuwenhoek built a simple microscope with a single lens to study blood, yeast, insects, and many different small objects. Leeuwenhoek was the first to describe bacteria and invented new strategies for smoothing and polishing microscope lenses that allowed curvatures that imparted magnifications of up to 270 diameters, the pleasant lenses available at that time. 18th century Technical innovations elevated microscopes, leading microscopy to become famous among scientists. Lenses that combined two types of glass decreased the chromatic effect, the annoying halos resulting from variations in the refraction of light. 1830 – Joseph Jackson Lister reduces spherical aberration or "chromatic effect" by demonstrating that various sensitive lenses used together at certain distances provided adequate magnification without blurring the image. This was the prototype of the compound microscope. Microscope can also be described as an optical instrument consisting of a lens or set of lenses for creating a magnified or enlarged image of a minute object. The simplest microscope is a magnifying glass composed of a single convex lens, which commonly magnifies about 5-10 times. The first microscope was built by the Dutch scientist Antony van Leeuwenhoek (1632-1723) who was actually once a reliable public regular and had a hobby of grinding lenses and making microscopic observations. He is said to have built nearly 400 easy microscopes that basically consisted of a single biconvex lens. Some of these microscopes had great powermagnification up to 200 times. Leeuwenhoek's microscope was once called easy because it only had one lens and had obstacles to the amount of magnification, not to mention the way they were constructed. However, the invention of the compound microscope helped develop the field of microbiology light years ahead of where it had been just a few years earlier. Once a second lens was brought to magnify the photo of the first lens. Modern lightweight compound microscopes, under superior conditions, can magnify an object 1000X to 2000X times. The specimen must be thin and vibrant enough to pass through the microscope and is mounted on a glass slide. In a compound microscope, light is transmitted and focused by a reflector and condenser that illuminate the object or specimen. The refracted light is then accumulated through a lens where the fundamental image of the object is modeled which is real, inverted and magnified. The eyepiece then similarly magnifies this principal photograph into a virtual, upright, magnified image. Although compound microscopes have two eyepieces, on the other hand they are not capable of producing three-dimensional or stereoscopic vision. This is because each of the eyes receives the same photo from the lens and the light beam is clearly divided into two. Robert Hook (1635-1703), an English scientist developed a compound microscope by using two lenses to achieve greater magnification. In Hooke's microscope. Most cells are too small to be observed with the help of the naked eye, the discovery of cells depended largely on the use of microscopes. Indeed, the very discovery of cells arose from the improvement of the microscope: Robert Hooke first coined the term “cell” following his observations of a piece of cork with an optical microscope in 1665. Using a microscope that magnified objects up to at around 300 times their actual size, Antony van Leeuwenhoek, in the 1670s, was able to observe a number of different cell types, including sperm, purple blood cells and bacteria. The inspiration of the cell principle with the help of Matthias Schleiden and Theodor Schwann in 1838 can be considered the beginning of contemporary cell biology. Microscopic studies of plant tissues with the help of Schleiden and of animal tissues through Schwann led to the same conclusion that all organisms are composed of cells. Shortly afterwards it was diagnosed that the cells no longer form, but arise exclusively from the division of pre-existing cells. Thus, the mobile phone has achieved its current goal as the quintessential unit of all living organisms thanks to observations made with the optical microscope. The limited resolution of the optical microscope, the evaluation of important points of the phone's structure required the use of more powerful microscopic methods, namely the electron microscope, developed once in the 1930s and first applied to organic samples by Albert Claude, Keith Porter and George Palade in the 1940s and 1950s. The electron microscope can acquire much greater resolution than that obtained with the optical microscope because the wavelength of the electrons is shorter than that of light. The wavelength of electrons in an electron microscope can be as low as 0.004 nm, about 100,000 times shorter than the wavelength of light seen. In theory, this wavelength should provide a resolution of 0.002 nm, however in practice such a decision is not possible, since the decision is not only determined by the wavelength, but also by the numerical aperture of the microscope lens. Numerical aperture is a limiting factor for the.