The first step in diagnosing a disease is to observe the particular signs and symptoms of this disease. Symptoms of HL include: Saying no to plagiarism. Get a tailor-made essay on "Why Violent Video Games Shouldn't Be Banned"? Get an original essay High fever Night sweats Persistent tiredness Severe itching Weight loss without clear explanation (10% of body weight) Painless swelling of lymph nodes in the neck, armpits, or groin High sensitivity to the effects of alcohol. There are two main types of Hodgkin lymphoma1 Classical Hodgkin lymphoma: The pathological hallmark of classical HL is the presence of multinucleated Reed-Sternberg which distinguishes this type from other types of HL - Classic HL includes nodular sclerosis which is the most common subtype, mixedcellularity, lymphocyte-depleted and lymphocyte-rich classical HL2 Nodular lymphocyte-predominant Hodgkin lymphoma: has other cell types called lymphocytic and histocytic cells instead of Reed-sternberg cells. We can say that it is important to diagnose the disease is to obtain information about the patient's personal and family medical history, so the patient undergoes some tests and procedures necessary for the diagnosis of Hodgkin's lymphoma, including: A physical examination: in this examination it is It is important to check for swollen lymph nodes, including the patient's neck, armpits, groin area, swollen spleen or liver. Blood tests: to check for the possibility of cancer through a blood sample taken from the patient's blood and examined in a laboratory. Imaging tests: to look for signs of HL in certain areas of the patient's body. This test includes X-ray, CT, and positron emission tomography. A lymph node biopsy procedure: to see if Reed-Sternberg cells which are abnormal cells are found within the lymph node. A bone marrow biopsy and aspiration procedure: removing a sample of bone marrow from the patient's hip bone to look for Hodgkin lymphoma cells. Other tests exist, but their use depends on the patient's situation. Hodgkin Lymphoma Staging: Determining the stage of the disease is very important as it helps determine the treatment options and prognosis of the patient. There are four stages of Hodgkin's lymphoma depending on how far the cancer has spread in the body. Stage I: The cancer is so limited that it does not grow beyond a lymph node or a single organ. Stage II: In this stage, the cancer has spread more widely. compared to stage I but remains limited to a section above or below the diaphragm. Stage III: In this stage the cancer spreads both above and below the diaphragm. Please note: this is just a sample. Get a custom paper from our expert writers now. Get a Custom Assay Stage IV: This stage is the most advanced of HL, and cancer cells in this stage are found in more than one portion of one or more organs and tissues .