Topic > The Final Process of Inflammation: Wound Healing

IntroductionWound healing is the final process of inflammation in which tissue architecture and function are repaired after injury.[1] Essentially, before wound healing occurs, inflammation occurs which helps eliminate the harmful agents and if elimination is not possible, the inflammation helps limit the effects caused by the harmful agents. Finally, it prepares the wound site for the healing process.[2]Image taken from: http://www.pilonidal.org/aftercare/wound_healing_infound.phpInflammationInflammation is a very important process in which it can dilute, destroy and even neutralize the injured party agents that cause the injury.[1] Without inflammation, the wound would never heal as infections persisted at the site of the injury.[1] There are two types of inflammation: acute inflammation and chronic inflammation. Acute inflammation Acute inflammation can be triggered by stimuli such as immune reactions, tissue necrosis, trauma and infections.[1] This is a rapid response to injury or foreign substances that transport leukocytes and plasma proteins to the site of injury.[1] Two major components of acute inflammation are vascular changes and cellular events.[1]• Vascular changes: Acute inflammation can cause vasodilation of blood vessels. Vasodilation of blood vessels results in increased blood flow to the site of injury, thus causing erythema (redness) and warm characteristics.[1] Vasodilation and increased blood flow then lead to an increase in intravascular hydrostatic pressure, allowing fluid (transudate) to flow from the capillaries into the tissues.[1] The fluid then accumulates in the extravascular spaces causing a condition called edema.[1]• Cellular Events:...... middle of paper ......ng is a chronic disease such as diabetes. The diabetic patient's wound is very difficult to heal as it involves different mechanisms. Therefore, it is very important for diabetic patients to take care of themselves to avoid injury as the wound healing process can be difficult. Works Cited1. Vinay Kumar, Ramzi S. Cotran and Stanley L. Robbins (2003) Robbins Basic Pathology (7th edition) Saunders2. Gerard J. Tortora, Berdell R. Funke and Christine L. Case (2006) Microbiology: an introduction (9th edition) Pearson3. S. Guo and LA DiPietro (2010) Factors influencing wound healing. J Dent Res 89(3): 219-2294. Eugene W. Nester, Denise G. Anderson, C. Evans Roberts and Martha T. Nester (2007) Microbiology: A Human Perspective (5th edition) McGraw-Hill5. Cathy Thomas Hess (2011) Checklist for factors affecting wound healing. Advances in skin and wound care 24(4): 192