This is an open wound in the lining of the stomach, intestines, or esophagus. Peptic ulcers have different names depending on their location. Such as gastric ulcer which are ulcers in the stomach. Duodenal ulcers are those found in the small intestine, while those found in the esophagus are known as esophageal ulcers. Duodenal ulcers are more common than gastric ulcers. While gastric ulcers are more malignant than duodenal ulcers. The most common cause of duodenal and gastric ulcers is H-pylori (Leik, 2014). People with peptic ulcers complain of episodic epigastric pain and burning, which may be short-term or long-term. The signs and symptoms of peptic ulcer are burning sensation or pain in the upper abdominal region, nausea, vomiting, belching, and bleeding, which may cause blood in the stool. This pain can occur one to three hours after consuming food or when the stomach is empty. The pain may worsen at night or occur intermittently for weeks. It should be noted that peptic ulcer pain can be relieved with food or by taking antacids. Diagnostic tests for peptic ulcer are a blood test to check for H-pylori, a stool sample is sent to the laboratory to see if there is blood in the stool, urea breath test is done to check for H-pylori, an upper endoscopy is performed to check if there is any problem with the digestive system, an upper gastrointestinal x-ray is performed to check the images of the stomach and intestines (Micromedex, 2016) . Treatment of peptic ulcer also depends on the cause. If H-pylori is identified, triple therapy with Biaxin, amoxicillin and proton pump inhibitor (PPI) is indicated for 6-8 weeks to allow the ulcers to heal. Quadruple therapy, including bismuth subsalicylate, Flagyl, tetracycline, and proton pump inhibitor (PPI) for 4 to 6 weeks or longer may also be indicated (Leik, 2014). However, if the condition is not caused by H-pylori, lifestyle changes are recommended,